Which anesthetic corresponds to a 1% solution with a max dose of 7-10 mg/kg?

• A. Lidocaine 1%
• B. Lidocaine with epinephrine 1% + 1:200,000 epi
• C. Procaine 1%
• D. Mepivacaine 1%

Answer: (C)

The main idea here is matching the drug’s typical maximum dose per kilogram to the stated 7–10 mg/kg range, taking into account both the drug’s concentration (percent solution) and how the dose changes with or without vasoconstrictor.

For a 1% solution, there are 10 mg of drug per milliliter. The ceiling of about 7 mg/kg corresponds to about 0.7 mL/kg. Among the options, procaine given as a 1% solution is classically dosed up to about 7 mg/kg, which fits the 7–10 mg/kg window described. Lidocaine (even at 1%) is more typically dosed at around 4.5 mg/kg without vasoconstrictor and about 7 mg/kg with epinephrine; its plain 1% form does not have a consistent 7–10 mg/kg ceiling. Mepivacaine 1% also tends to have a lower plain ceiling (often around 5 mg/kg, higher with vasoconstrictor), not a fixed 7–10 mg/kg. Therefore, procaine 1% best matches the stated dose range.

In modern practice, procaine is used less frequently, but this dosing relationship is why it’s the correct choice in this context.