Triamcinolone and betamethasone are longer-acting and more potent than hydrocortisone.

• A. They are shorter acting than hydrocortisone
• B. They are longer acting and more potent than hydrocortisone
• C. They are identical in potency to hydrocortisone
• D. They are not used topically

Answer: (B)

Topical corticosteroids vary in how strong they are and how long their effects last on the skin. Hydrocortisone is a low-potency steroid with relatively short-lasting action, which makes it suitable for mild irritation or sensitive areas. Triamcinolone and betamethasone are synthetic corticosteroids with greater anti-inflammatory effect and longer duration when applied to the skin. Betamethasone tends to be among the higher-potency options, while triamcinolone is potent enough to be more effective than hydrocortisone in many cases, and its duration is longer as well. Because of this combination of higher potency and longer action, the statement that they are longer-acting and more potent than hydrocortisone is true. The other options conflict with these facts (they are not shorter-acting, not identical in potency, and they are used topically in appropriate preparations).